Work Text:
Author - Dr YuriOnCat
Journal of Behavioral Incest Endocrinology, Volume 37, 2025
Materials and Methods:
A cohort of 120 partner dyads with varying degrees of genetic relatedness (biological siblings, first cousins, and genetically unrelated partners) participated in the study. Neurophysiological responses were assessed using functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). Additionally, hormonal assays from saliva and plasma samples were conducted to measure variations in endocrine activity during pre-, peri-, and post-coital phases.
Results:
1. Enhanced Activation of the Hypothalamic-Pituitary-Adrenal (HPA) Axis:
Dyads with a consanguinity coefficient ≥0.5 exhibited a 68% increase in oxytocin and vasopressin release compared to controls. This heightened endocrine response correlated positively with subjective reports of pleasure, assessed via Visual Analog Scales (VAS).
2. Hyperactivation of the Amygdalo-Insular Complex:
fMRI analyses revealed increased activity within the anterior insula, a region implicated in the integration of emotional and visceral signals. Participants from genetically related dyads displayed insular activation 3.2 times higher than non-related counterparts, suggesting a mechanism of "Implicit Phenotypic Resonance" (IPR), wherein recognition of shared genetic markers elicits an amplified emotional response.
3. Dopaminergic Modulation in the Mesolimbic System:
Elevated dopamine release (↑55%) was observed in the nucleus accumbens among genetically similar partners, particularly within sibling dyads. Simultaneously, enhanced activity in the orbitofrontal cortex indicated a reinforcement of the emotional salience associated with the act.
4. Increased Endocannabinoid Production:
Post-coital assays revealed a significant rise in anandamide and 2-arachidonoylglycerol (2-AG) levels (+47%) in genetically related dyads compared to the control group. This surge likely contributes to prolonged sensations of satisfaction and relaxation, mediated by endocannabinoid interactions with the limbic circuitry.
Discussion:
Our findings suggest that genetic proximity serves as a co-agonist in the modulation of neuroendocrine responses linked to sexual pleasure. The underlying mechanism may involve synergistic activation of oxytocinergic and dopaminergic systems, facilitated by unconscious recognition of shared phenotypic markers. This phenomenon, herein termed "Neurogenetic Endocrine Resonance" (NER), appears most pronounced in sibling dyads, where genetic congruence surpasses a critical threshold for hedonic circuit activation.
Conclusion:
This study identifies a significant correlation between genetic similarity and heightened sexual pleasure, offering new insights into the intersection of biological inheritance and hedonic experience. Further research is warranted to delineate the neurobiological underpinnings of NER and its implications for understanding complex human relational dynamics.
Keywords: genetic proximity, sexual pleasure, neuroendocrinology, oxytocin, dopamine, neurogenetic resonance
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Conflicts of Interest: None declared.
Funding: Supported by the International Center for Research in Behavioral Neurobiology (ICRBN).